Undergraduate Research & Scholarships

Neha Lozano

Analyzing Stem Cell Fate in Lung Organoids via Genetic Perturbation

This project aims to study the nuances of stem cell differentiation by modifying genetic expression within human lung organoids. Using techniques such as lentiviral gene transfection and CRISPR-Cas9-mediated knockdown, we will alter various transcription factors to observe their effects on gene regulatory networks and cell fate decisions. These findings will hopefully bolster the efficiency of stem cell-based regenerative therapies by allowing us to gain a better understanding of what drives differentiation versus the maintenance of stem-like states.

 

Message To Sponsor

Thank you so much for this incredible opportunity and for supporting me in my journey of pursuing scientific research! I have always been fascinated by stem cells, and participating in this project through the URAP program has given me meaningful exposure to a hands-on wet lab environment, allowing me to develop the skills necessary to pursue a career in the field of regenerative medicine. I’m truly grateful for your generosity and look forward to making the most of this summer experience!