Alina Boltunova L&S Sciences
Developmental Emmetropization in Guinea Pigs
Emmetropization is a normal developmental process in which the eyes growth is regulated to achieve a match between eye length and its refractive power. It results in the reduction of refractive errors present at birth and has been observed in all animal species, including humans, studied thus far. The guinea pig is increasingly used to model myopia (near-sightedness), but there appear to be differences between guinea pig strains in their susceptibility to myopia-inducing stimuli. To understand the origin of these differences, I plan to compare the emmetropization of different strains of guinea pigs by tracking changes in their ocular dimensions and refractive error during the course of their development.