Annie Yau Rose Hills
Survey of Gestational Diabetes Mellitus and Pregnant Women in Mysore, India
Gestational Diabetes Mellitus (GDM) is a condition of glucose intolerance onset during pregnancy, and is associated with increased risk of complications during pregnancy and increased likelihood of bearing overweight infants. Worldwide GDM affects approximately 4% of women, and studies suggest that GDM may be more common in Indian women. Early screening and treatment of women with mild GDM has been shown to reduce the likelihood of complications during pregnancy and prevent the onset of type-2 diabetes. Given the growing public health concern of GDM and type 2 diabetes in India, there is a pressing need to find a simple and feasible test for GDM. Relaxin is an insulin homologue produced in pregnant women, and has been demonstrated to be significantly higher in diabetic women compared to their normal counterparts, indicating that relaxin could provide a convenient marker for GDM. This project aims to determine whether elevated plasma levels of relaxin correlate with increased risk of GDM in pregnant Indian women. The development of a simple and cheap GDM test has the potential to provide widespread GDM prevention to communities with limited access to healthcare worldwide.