Jacob Richards Rose Hills
The Dynamic Resting Brain: Dopamine-Dependent Changes in Functional Connectivity of Intrinsic Networks
The brain is a system of cells that electrically interact with each other in complex ways. Using functional magnetic resonance imaging (fMRI) on a human at rest or doing a task, we can identify clusters of cells that work together to transmit electrical messages to other clusters of cells. These functional networks allow us to connect what is happening physiologically in the brain to mental phenomena. It is useful to find a baseline organization of functional networks in the brain to characterize what changes occur when a human begins a task and what happens when the mind wanders” at rest. I will look at subjects at rest with differing levels of brain dopamine (an important chemical for brain function) to identify a collection of functional networks common across subjects and present at both dopamine levels. This will provide insight into intrinsic brain activity as well as direction toward an understanding of the neural correlates of the unconscious mind.