Jordan Tsai Rose Hills
A Neurospora crassa Serine-threonine Kinsae Involved in the Transition to Cellulolytic Metabolism
I am studying the degradation of plant biomass in the fungal model organism Neurospora crassa. The study of plant biomass degradation is important because it will both help us understand the molecular mechanisms behind this essential ecological process, and may also aid in the production of biofuels derived from lignocellulosic biomass, which could serve as an alternative to petroleum based fuels. Previous genetic analysis has implicated a N. crassa serine-threonine kinase in the cellulolytic metabolism pathway, but its molecular mechanisms remain unknown. I want to investigate the role of this kinase in cellulolytic metabolism, and how the primary structure relates to its function as a signal transducer.