Pupil Response & Recovery Rates and Clinical Effects of Low Dose Atropine
Myopia, or near-sightedness, is one of the largest epidemics affecting children and adults worldwide. Atropine has been used as a dilating agent for various clinical purposes, yet at low doses has been found to decrease the progression of myopia in children. This summer, I will be focusing on two projects: 1. Does applying two drops of 0.01% atropine sulfate solution cause the same clinical effects as one drop of 0.02% atropine? 2. How quickly do the pupil responses and ciliary muscles recover following a dose of 0.01% atropine, 0.02% atropine, and 0.05% atropine?
By studying the effects of pupil response and recovery rates at various doses, we are better able to approach the use of atropine as a clinical treatment for myopic children.