Alex Oanta
Metal-promoted reactions are frequently utilized in the syntheses of complex organic products that are vital to the pharmaceutical and petroleum industries. With the intention of discovering new, more efficient chemical pathways to otherwise inaccessible or costly organic chemicals, many inorganic chemists devote their careers to the synthesis and study of discrete molecular compounds centered on a well-defined metal ion. Previous reactivity studies on such molecular metal-based compounds support the conjecture that electronically saturating the valence orbitals of a metal with multiple ligands can enhance the reactivity of the electrons involved […]
Kamran Ahmed
The mammalian target of rapamycin complex 1 (mTORC1) is a protein complex that activates protein synthesis, modulates cell growth and proliferation, and regulates autophagy. Loss-of-function mutations in the TSC1 or TSC2 genes, which negatively regulate mTORC1, result in complex hyperactivity causing the syndromic neurodevelopmental disorder Tuberous Sclerosis Complex (TSC). TSC patients have a wide variety of clinical presentations including high comorbidity rates with neuropsychiatric disorders in which the dopaminergic system has been implicated. Little is known about the impact of mTORC1 disruption on the dopaminergic system. Previous work showed that […]
Arohi Saxena
Use-dependent learning is a motor learning process that is thought to arise from the repetition of a specific movement pattern. Use-dependent learning is thought to underlie the refinement of motor skills, such that well-practiced actions become more accurate and consistent (the practice makes perfect phenomenon); however, this learning process also comes at the cost of biasing subsequent actions to be more similar to practiced ones. It was initially assumed that pure repetition of a movement was the only necessary condition to drive use-dependent learning, however recent studies suggest that some […]
Jessica Bonnar
In eukaryotes, an essential growth regulator is a multi-subunit, plasma membrane(PM)-associated protein kinase, the Target of Rapamycin Complex 2 (or TORC2). Work using Saccharomyces cerevisiae has established that TORC2 is responsible for controlling processes that preserve PM homeostasis and that regulate actin polymerization. Studies have shown that the localization of TORC2 to the plasma membrane is essential for the complex’s function. However, little is understood about the processes that regulate the assembly, maintenance and activity of TORC2 itself. Avo3, a TORC2 subunit necessary for maintaining stability of the complex, contains […]
Dalila Robledo
According to the Standard Model, all baryonic matter is predicted to have a corresponding antiparticle. From this premise, we currently dont understand why we observe more matter than antimatter, making the study of antimatter a fascinating subject. My research project is with the ALPHA experiment at CERN, which produces antihydrogen. Composed of an antiproton and a positron bind together, antihydrogen is the matter counterpart of hydrogen. Because of its neutrality and correspondence with the hydrogen atom, it is a desirable system for experimental study. My summer project involves numerical simulations […]
Sheng-Yu Wang
Over this summer, I will be doing research on autonomous driving focusing on integrating and synchronizing data from laser radar sensor, which is also known as LIDAR, and multiple camera view. Autonomous driving has been a popular research subject recently, and it is really important to improve accuracy for the decision making by the algorithm. Since the output decision of the autonomous driving system is based on the information which sensors received from the environment, the accuracy of the decision making relies heavily on the integrity and the richness of […]
Jonathan Qu
While speciation (the formation of new species) is often thought of as occurring through the splitting of one species into two, species can arise through other mechanisms, such as allopolyploidy. Allopolyploidy occurs through the formation of a hybrid between two species, followed by genome duplication. This mechanism of speciation is common in plants, including in crop plants. While artificial allopolyploid plants have been studied in the laboratory, allopolyploidy remains understudied in natural populations. Polystichum californicum is a fern species thought to have originated via multiple independent allopolyploidization events throughout its […]
Kiran Brar
While the unbalanced sex-based division of labor has been explored in various parts of the developing world, it remains largely unstudied in Punjab (Northwest India). Punjab is a predominantly agricultural society with diverse family organizational forms, including joint and extended families. I will examine how the division of labor amongst heterosexual couples in Punjab, India is influenced by gender, religion, education, and area of residency. I will conduct 20 in-depth interviews in two cities and two to three rural villages, divided evenly into the following four groups: 1) rural and […]
Weirui Xiao
Women who are on birth control pills are at higher risk for Chlamydia trachomatis (Ct) infection than women not on birth control pills. There is also evidence that women whose endometrium is decidualized during the secretory phase of the menstrual cycle are more susceptible to Ct infection compared to women in other phases of their cycle. However, the basis for this susceptibility to Ct infection is poorly understood at a molecular level. We have previously shown that an increase in the availability of the fatty acid oleic acid (OA) to […]
Keren Lev
We propose to conduct research exploring potential cognitive adaptations in children who come from less wealthy and/or educated homes (low socioeconomic status, SES). Previous research indicates that lower-SES environments expose children to stressors including neighborhood crime and loud, crowded home environments. Such stress has been associated with academic struggles and poor health. We explore whether children coming from low SES households may, in fact, have particular strengths; specifically, adaptive auditory abilities allowing them to learn from multiple stimuli at once. In the study, we will have both low- and high-SES […]