Kangying Connie Wu
Twenty-five years of reform in China have impacted virtually all corners of social life. During the Mao era, urban neighborhood mediation committees helped to resolve disputes and conserve social harmony and stability in the cities. Today, the physical and social structures of China’s cities have changed dramatically, raising questions about whether these remnants of the Mao era can continue to play the same role as before. Connie Wu’s research will explore this question by comparing the present role of the mediation committees in traditional, Maoist, and modern neighborhoods of Beijing. […]
Carolina Dallett
The Arabidopsis thaliana genome has been sequenced, allowing use of sophisticated tools for genetic studies. It is known that DME controls gene transcription, encodes a DNA glycosylase, and has homologous proteins in the Arabidopsis genome as well as orthologs in rice, wheat, and maize. We do not know, however, how this is accomplished. Carolina will investigate the DEMETER protein, essential for seed viability in Arabidopsis, using molecular tools and genetics. The project has two phases: 1) To determine if the family member proteins can replace the DME protein; 2) determine […]
Lorraine M. Wang
The ability of cells to respond to extracellular signals is mediated by signal transduction networks that almost invariably include a cascade of protein kinases. One family of protein kinases that is universally conserved in eukaryotes is called the p21-activated protein kinases (PAKs). The genome of Saccharomyces cerevisiae has revealed a closely related PAK-type protein kinase called Cla4. Cla4 is required for the proper assembly of a novel cytoskeletal structure that is essential for cytokinesis thereby providing an important checkpoint in the highly regulated cell cycle. Lorraine will be investigating the […]
Jacob Coakley
Jacob will write, as an independent study project in the English department, a full-length play with a double narrative. This duality of structure will allow Jacob to experiment with various forms of multi-media and digital technology available in a modern theatrical production in an effort to explore questions of human subjectivity raised by media theory. To accomplish this, Jacob will develop the script in dialogue with an actress over the summer in New York City, while observing the techniques and technology of several avant-garde theatre companies in NYC already doing […]
Jessica Stevenson-Stewart
Jessica will examine the travel writings and photographic works of Gertrude Bell, an Orientalist scholar who served British intelligence in the Middle East before and after World War I. Bells extensive imperialist project resulted in volumes of writings and photographs that document these archeological and diplomatic expeditions. Addressing how Bell used such representations to validate her scholarly authority, Jessica will study the problems of authorship peculiar to the photographic medium. Taking into account post-structural and post-colonial theories, Jessica will be asking how Bell utilized the mechanistic gaze of the camera […]
Susannette Burroughs
The “Last Judgment” (“Golden Gate”) mosaic is located on the southern exterior of Saint Vitus’ Cathedral at Prague, a fourteenth century Gothic monument. The mosaic was a framing device for activity which occurred before and behind it: it functioned to separate and relate sacred and secular pasts and presents as a permeable barrier, one which separated and joined secular and ecclesiastical realms of functionality. This project is an investigation of the high degree to which this mosaic promoted powerful localized and international messages of imperial, dynastic, and religious power in […]
Daniil Prigozhin
Dengue virus (DEN) causes the most widespread life-threatening arboviral disease in humans, with an estimated 2.5 billion people at risk worldwide. Despite the global morbidity and mortality, DEN specific vaccines and therapies currently do not exist, and both protective and pathogenic roles of the immune system in DEN infection need further investigation. The Harris laboratory has recently demonstrated that the interferon (IFN)-dependent immunity is essential and more important than T and B lymphocyte-dependent adaptive immunity in controlling primary DEN infection in mice. IFNs are proteins that are secreted by vertebrate […]
Morgan Burke
Morgan’s fascination with neurobiology led her to join the laboratory of Prof. Irving Zucker, where she has been studying the neuroendocrine basis of seasonal rhythms. Siberian hamsters, like most mammals, restrict production of offspring to the spring and summer. They do so by measuring day length. Neural and endocrine tissues decode day length by measuring the duration of nocturnal melatonin secretion. Morgan’s study, which will serve as the basis of her senior thesis, will assess whether the dorsomedial hypothalamic nucleus, a brain melatonin target tissue, is a necessary and sufficient […]
Andrew Pascall
With costly Superfund cleanups making headlines recently, companies have realized that the most financially prudent solution to dispose of hazardous waste is not to produce it at all. In order to reach this goal, new heterogeneous catalysts will need to be developed that have high selectivity and activity in non-hazardous solvents. Andrews project will focus on the Knoevenagel condensation, a reaction important to industries from food additives to textiles. Generally, this reaction is performed in an organic solvent, many of which are carcinogenic. Andrews research will focus on the design […]
David H. Nguyen
Activation of the proto-oncogene c-Src, a tyrosine kinase, is evident in major cancers such as breast and colon. C-Src activates substrates that serve important roles in controlling growth, survival and motility of cells. Activation of c-Src is known to cause transformation, the process by which normal cells become cancerous. David seeks to elucidate how v-Src, a viral constitutively active form of c-Src, regulates Protein Kinase Cz (PKCz), which is a protein involved in control of growth and survival. The Martin lab has shown that v-Src can tyrosine-phosphorylate PKCz and that […]